The Eastern United States, the American East, or simply the East is traditionally defined as the states east of the Mississippi River. The first two tiers of states west of the Mississippi have traditionally been considered part of the West, but can be included in the East today; usually in regional models that exclude a Central region. The estimated population of the eastern United States as of 2006 is about 148,000,000.

Major population centers
The following is a list of the 24 largest cities in the East; it does not reflect any preferencial treatment to any city not listed:
New York City

Chicago

Philadelphia

Miami

Indianapolis

Jacksonville

Columbus

Memphis

Baltimore

Charlotte

Nashville

Boston

Washington, D.C.

Milwaukee

Louisville

Atlanta

New Orleans

Cleveland

Virginia Beach

Minneapolis

Cincinnati

Tampa

Pittsburgh

Toledo

Newark

Buffalo

St. Paul

Detroit


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